Abstract: The use of mechanical drilling in accessing energy resources stored in deep and hard rock formations is becoming increasingly challenging. Thus, laser irradiation has emerged as a novel drilling method with considerable in this context. This study examines the variation of rock fracture length, fracture tortuosity, hole size, and rock breaking efficiency for a different number of holes and laser power, based on the constant total energy of laser irradiation. As indicated by the results, increasing the laser power increases the laser intensity, which helps increase the hole diameter and depth. Moreover, for the same laser power, increasing the number of irradiated holes reduces the laser energy absorbed by each hole, which is not conducive to increasing the hole depth. As the number of holes increases, the mass loss of the rock also increases, while both specific energy (SE) and modified specific energy (MSE) decrease. When the number of holes remains the same, the mass of the shale removed by low power is less than that removed by high power, while SE and MSE have an inverse relation with power. Therefore, high laser power and multiple-hole irradiation are more conducive to rock breaking. Besides, the fracture length and fracture tortuosity of the rock irradiated by the low laser power will increase first and then decrease with the increase in the number of holes, and reach the peak value when the irradiation takes place through three holes. When a high-power laser irradiates the rock, the fracture length and tortuosity will increase with the increase in the number of irradiation holes. This is because a rock irradiated by low power dissipates more energy, with the result that the energy absorbed by the sample with four irradiation holes is not enough to break the rock quickly. This study is expected to provide some guidance to break rock for drilling deep reservoirs and hard rock formations using laser irradiation.